2024年3月21日发(作者：夕凯风)

专利内容由知识产权出版社提供

专利名称：4-Substituted pyrazoles

发明人：Eike Moller,Karl Meng, deceased,Egbert

Wehinger,Harald Horstmann,Friedel Seuter

申请号：US05/766235

申请日：19770207

公开号：US04113872A

公开日：19780912

摘要：Pyrazoles of the formula ##STR1## wherein R is hydrogen, alkyl, aryl, aralkyl,

trifluoromethyl or a heterocycle;

. 1 is aryl or aralkyl unsubstituted or substituted by halo, trifluoromethyl, alkyl,

alkoxy or nitro; or a halo-substituted alkylthio moiety;

.2 is lower alkyl; phenyl; or benzyl;< P>

R. sup.3 is aryl unsubstituted or substituted by alkyl, alkenyl, alkoxy, halo,

trifluoromethyl, trifluoromethoxy, mono- or di- alkylamino, nitro, cyano, carboxamido,

sulphonamido or .n -alkyl; phenyl having fused thereto a 5- to 7-membered

isocyclic or heterocyclic ring, said heterocyclic ring having 1 or 2 oxygen or sulphur

heteroatoms; or pyridyl; and

.4 is unsubstituted or substituted carboacyl or sulphonyl; are useful for their

diuretic, saluretic, antihypertensive and antithrombotic properties.

申请人：BAKER AKTIENGESELLSHAFT

代理机构：Jacobs & Jacobs

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2024年3月21日发(作者：夕凯风)

专利内容由知识产权出版社提供

专利名称：4-Substituted pyrazoles

发明人：Eike Moller,Karl Meng, deceased,Egbert

Wehinger,Harald Horstmann,Friedel Seuter

申请号：US05/766235

申请日：19770207

公开号：US04113872A

公开日：19780912

摘要：Pyrazoles of the formula ##STR1## wherein R is hydrogen, alkyl, aryl, aralkyl,

trifluoromethyl or a heterocycle;

. 1 is aryl or aralkyl unsubstituted or substituted by halo, trifluoromethyl, alkyl,

alkoxy or nitro; or a halo-substituted alkylthio moiety;

.2 is lower alkyl; phenyl; or benzyl;< P>

R. sup.3 is aryl unsubstituted or substituted by alkyl, alkenyl, alkoxy, halo,

trifluoromethyl, trifluoromethoxy, mono- or di- alkylamino, nitro, cyano, carboxamido,

sulphonamido or .n -alkyl; phenyl having fused thereto a 5- to 7-membered

isocyclic or heterocyclic ring, said heterocyclic ring having 1 or 2 oxygen or sulphur

heteroatoms; or pyridyl; and

.4 is unsubstituted or substituted carboacyl or sulphonyl; are useful for their

diuretic, saluretic, antihypertensive and antithrombotic properties.

申请人：BAKER AKTIENGESELLSHAFT

代理机构：Jacobs & Jacobs

更多信息请下载全文后查看